If you’re starting or considering semaglutide, you likely have questions about this new medication. One common question is, “Does semaglutide need to be refrigerated?” and ‘’how long does compounded semaglutide last in the fridge?’’ The answer depends on its form. Injectable semaglutide, like Ozempic and Wegovy, should be kept in the fridge before first use. Oral semaglutide, known as Rybelsus, can be stored at room temperature.
Like all medications, proper storage is key to making sure semaglutide works safely and effectively. This guide will explain compounded semaglutide ,how to store it correctly , about its expiration and effectiveness.
Understanding Compounded Semaglutide
Compounding pharmacies and facilities make compounded semaglutide injections instead of pharmaceutical manufacturers. A compounded medication is a medication that is customized and available from a pharmacy specializing in compounding. These are exacerbated by licensed pharmacists in a controlled environment. The raw material and active ingredients are sourced from reliable suppliers by licensed pharmacies. These are often prescribed when FDA-approved medications, doses, and forms aren’t available. Moreover, it is much cheaper than the non-compounded semaglutide.
Moreover, it is produced in small batches to meet patients’ needs. The compounded preparation containing semaglutide has not been tested to the same extent as a commercial product. So it’s important to get from a reliable source.
The importance of proper storage
Semaglutide should be stored correctly to remain effective. When not stored properly, its chemical composition can change. Be sure to keep it at the recommended temperature in order to keep it stable.
Semaglutide works well when stored properly. The effectiveness of this product can be reduced if it gets too hot or is exposed to sunlight. As a result, it won’t work properly.
In order for semaglutide to remain effective throughout its shelf life, it must be stored properly. It helps control blood sugar and aid weight loss. Make sure you follow the storage instructions provided by your healthcare provider or pharmacist.
How long does compounded semaglutide last in the fridge?
The refrigeration needs for semaglutide depend on its form.
- Injectable semaglutide (Ozempic, Wegovy) must be refrigerated until first use.
- After opening, Ozempic can stay at room temperature for up to 56 days.
- Wegovy can be kept in its carton at 46 °F to 86 °F for 28 days if necessary.
- Oral semaglutide (Rybelsus) does not need refrigeration and should be stored in a dry place at room temperature.
What happens if semaglutide is not refrigerated?
Improper storage can affect medication effectiveness and safety.
Reduced effectiveness
If injectable semaglutide is kept at the wrong temperatures, its structure can break down. This makes it less potent, which can lead to poorer blood sugar control and less weight loss.
Safety concerns
Using semaglutide that has been stored incorrectly can pose safety risks:
- It may cause unexpected side effects.
- Bacteria could grow in damaged solutions.
- Chemical changes may create harmful byproducts.
Injectable Semaglutide: Check for cloudiness, discoloration, or floating particles. The solution should be clear and colorless.
Oral Semaglutide: Look for changes in the tablet’s appearance, strange smells, or crumbling. If you are unsure, ask your pharmacist before using it.
Does semaglutide expire? How do you know?
There is an expiration date for compounded semaglutide. Here’s a simpler guide for storing semaglutide:
1. Label and keep semaglutide in its original packaging.
2. Store it in the fridge between 36-46°F (2-8°C).
3. Place it away from the cooling element to avoid freezing.
4. Keep the pen or vial upright to prevent leaks.
5. Regularly check the expiration date and throw away any expired or unused medication.
Following these steps will help keep semaglutide effective.
How to store compounded semaglutide in the fridge?
The best way to keep it effective for as long as possible is to store it properly. Keep it refrigerated at home. Make sure you keep your medication at the right temperature while traveling by using an insulated cooler or a medication travel case. If you have multiple pens or vials, use the ones that are about to expire first. As a result, you won’t waste any medication by accident. Avoid the hassle of dealing with expired medications by following these simple steps.
Final Thoughts
The storage of compounded semaglutide plays an essential role in maintaining its efficacy. Remember to refrigerate injectable formulations to preserve their potency, while the oral version allows for easier storage at room temperature. Regularly check on your medication to ensure it is within its expiration period and remains in optimal condition. Taking these steps will help you achieve the best possible results in your weight loss or diabetes management efforts.




